Trends among adolescents continue to be discouraging in terms of career and college readiness based on National Assessment of Educational Progress (NAEP) achievement reports and high school graduation rate data. In response, this article presents five goals and eight strategies we have engaged in during a seven-year research study focused on building college and career readiness among adolescents. During our final year of helping students build college and career readiness, we found associated improvements in their academic-related perceptions, beliefs, and strategies; positive personal achievement and goal orientation; rising perceptions of college; improving trends in academic performance; and stronger perseverance in high school when compared to a control group. Because the students in this study have not completed their high school senior year, we do not have data that predict their college acceptance or career readiness. (Contains 3 tables.)