The countries of the Eastern Partnership (EaP) -- an initiative between the Member States of the European Union and Eastern European and South Caucasus countries -- are navigating significant challenges while striving for sustainable economic growth and social cohesion. Education plays a crucial role in unlocking the potential of digitalisation and the green transition, offering pathways for economic diversification and innovation. This report, developed in co-operation with the European Commission and UNICEF, analyses PISA data for the EaP countries and economies that participated in PISA 2022: Baku (Azerbaijan), Georgia, Moldova, and Ukrainian regions. It identifies the strengths and challenges within these education systems and provides recommendations on how to build more resilient, equitable, and high-performing systems to support economic and social goals. This report will be of particular interest to policymakers and stakeholders dedicated to advancing education across the Eastern Partnership region.