In this paper, TNTP reveals five interconnected factors of mobility that young people need in order to thrive: a strong academic foundation, career-connected learning, opportunities to build social capital, personal support in their lives, and civic engagement in their community. These five factors do not work in isolation. Instead, they must be woven together into coherent support for young people, with coordinated efforts from the many systems that shape young people's lives. TNTP's new Research Center of Excellence is currently studying each factor of mobility and, critically, exploring the connections between them. This report, "The Opportunity Makers," is the first chapter of ongoing mobility research. It identifies how to build a strong academic foundation for all students, particularly for historically marginalized groups like students of color, students experiencing poverty, multilingual learners, students with disabilities, and students with learning and thinking differences.