Anatomy and Physiology (ANP) courses are a standard requirement for effectively all undergraduate healthcare programs in the country. A large majority of students enrolled in these courses are attending 2-year colleges and pursuing nursing certifications and recertifications. Traditionally, the instructional method and content of Anatomy and Physiology courses is based on traditional instructor focused lecture platforms, with laboratory content centered on physical modeling and manipulation. As technology advances and the continued impacts of the COVID-19 pandemic shift our educational platform methods, larger scale considerations for what merits student success are considered. Comparison of course success in ANP and summative assessment success on nursing entrance exams, illustrates that the platform of content instruction is potentially less meaningful and that larger scale considerations may be necessary for assessment skills and the transition of ANP content knowledge, particularly with long term COVID-19 impacts on education. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://bibliotheek.ehb.be:2222/en-US/products/dissertations/individuals.shtml.]