Simulation technologies are used in simulation-based education however retention of knowledge, skills, and abilities have yet to be determined. This study evolved from areas of research that do not adequately show or address measurements of retention of knowledge, skills, and abilities in the professional environments after training with simulation technologies. The research question was "what is the perception of health care professional's long-term retention of KSAs using simulation technologies?" A generic qualitative analysis was best for investigating and developing an understanding of individual experiences and identifying how those experiences affected perceptions of the participants. The participants in the study were health care professionals who had participated in simulation-based education using simulation technologies within the last 2 to 5 years. Eleven participants were interviewed. Semi-structured interviews were conducted using the VOIP Zoom Meeting platform. After the interviews, analysis of the data, coding and theming were conducted. The analysis produced 3 themes from the data collected. The first theme is retention of knowledge, skills, and abilities; second theme is realism of simulation technologies; and the third theme is confidence in learning and practicing. The findings of the research provided the foundation for future research in simulation technologies and how retention is affected. Participants explained that KSA's were affected positively with the use of simulation technologies, had positive perceptions with the use of simulation technologies and indicated comfort and confidence levels increased. However, there needs to be more studies conducted at different intervals to provide more concise data collection and results for providing more analysis. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://bibliotheek.ehb.be:2222/en-US/products/dissertations/individuals.shtml.]