This report is focused on the uptake of GCSE subjects in England in 2022. Uptake in a GCSE subject is defined as the number or percentage of students at the end of Key Stage 4 (KS4) taking the subject. This report was produced using publicly available data from the Department for Education's (DfE) "Find and compare schools in England" service. The dataset consisted of KS4 results in all subjects provided by each school in England. Other school information, such as schools' sex composition, admissions policy, and the number of disadvantaged pupils at the end of KS4 were also available. Only GCSEs (9-1) full course (both single and double award) were counted for this report. In this report, GCSE uptake is presented by the following school classifications: school type, school attainment, school deprivation level, and school sex composition.