Understanding test-taking strategies (TTSs) and the variables that influence TTSs is crucial to understanding what reading comprehension tests measure. We examined how passage and student characteristics were associated with TTSs and their impact on response accuracy. Third (n = 78), fifth (n = 86), and eighth (n = 86) graders read and answered questions associated with six passages. Eye-movement records were used to code TTSs. Results indicated that TTS choice was related to passage and student characteristics. Passage characteristics that make comprehension more difficult resulted in more students choosing a TTS that did not involve reading passages in their entirety before answering questions. TTSs encompassing reading passages in their entirety before answering questions resulted in higher accuracy for 5th and 8th graders. Understanding TTS choices can aid our understanding of the processes measured by reading comprehension tests, what TTS should be encouraged, and what contributes to tests producing different outcomes.