The Chancellor of the Oklahoma state system of higher education has focused on two overarching objectives: expanding workforce development efforts and creating paths to a better life for Oklahomans. Oklahoma public institutions and elected officials are partners in developing an educated, engaged workforce prepared to meet the state's current and future employment needs, particularly in the areas of healthcare, teacher education, engineering, computer science, and other STEM fields. Included in this annual report are: (1) Role of the State Regents; (2) Higher Education Update; (3) Campus Rankings; (4) State System Fast Facts; (5) Key Initiatives; (6) Affordability; (7) Enrollment; (8) Outcomes; (9) Workforce Development; and (10) Institutional Highlights. [For the 2021 report, see ED624700.]