The present work is the report of an intern, who through the theme: "Drugs" shows the importance of the use of didactic sequence in the teaching of chemistry for the construction of concepts. The content was applied in classes of the 3rd year of high school, in a public school, in the city of Apucarana - PR. In this sense, the main types of drugs known in daily life were contextualized, soon after the properties of organic compounds and nitrogen compounds have been addressed. The relationships established through the theme resulted in a greater interest of the students in the didactic content, since it was possible to see practical results. Some did not know much about the chemical composition of the drugs, others even had contact, or knew someone who has already used some substance. The theme is part of the day-to-day and in this way, they were able to build and develop critical thinking at the end of the process. [For the complete proceedings, see ED631021.]