Background and Aim of Study: The mental health and social adaptation of young students and cadets in wartime conditions is a new and understudied problem. The aim of the study: to identify the particularities of psychological well-being and social adaptation of students and cadets in wartime conditions. Materials and Methods: Our study was conducted among the students and cadets of two Ukrainian universities (KNUIA, UzhNU) in 2023, February. 327 participants were divided into 3 groups: 1) 112 cadets whose permanent disposition was changed in Ukraine; 2) 108 students who were displaced and who are in Ukraine and EU countries; 3) 107 students who did not change their place of permanent residence and who are in Ukraine in the combat zone or near it. The 28-item General Health Questionnaire (GHQ-28) to assess psychological well-being and emotional stability, and the Social Support Questionnaire (F-SozU K-22) to determine the particularities of emotional support, practical support, and social integration were used in the study. Appropriate internal consistency values (Cronbach a between 0.817 and 0.903) were found for both scales. Results: Group 1 has the best general health indicator: 1.65 times better than Group 3. The levels of somatic symptoms, anxiety and insomnia are lower in Group 1 (practically the same in women and men), and higher in Group 3. The highest rates of social dysfunction are found in Group 3. Men in all groups have more pronounced social dysfunction; women in all groups have more pronounced severe depression. Group 1 total perceived social support is 1.89 times better than Group 3. Emotional support, social integration are highest in Group 1, practical support is highest in Group 2. Conclusions: The lowest levels of psychological well-being and social adaptation were found in Group 3. This is probably due to uncertainty about the future, constant instability and insecurity. Teachers and psychologists are urged to consider the identified psychological and social peculiarities in the educational and clinical process when dealing with young students.