The Ithaka S+R Library Survey has examined leadership and strategic perspectives in the field by surveying library deans and directors nationally on a triennial basis since 2010. The research project's overarching goals are to provide the library community with a valuable data source to inform decision making and track the emerging opportunities and challenges leaders face in steering their organizations. In fall 2022, we surveyed library leaders at not-for-profit four-year academic institutions across the United States, with a response rate of 42 percent based on 612 responses. In this sixth iteration of the project, we continued to track high-level issues of strategy, leadership, budget, staffing, and institutional alignment. We also introduced new batteries of questions related to broader trends in higher education, including remote and hybrid learning, talent retention, and research data management, and expanded our coverage of open access and diversity, equity, inclusion, and accessibility (DEIA). [For the 2019 report, see ED628831.]