Across the United States, many school leaders are engaging in systematic screening processes as part of integrated, tiered systems of support to meet students' multiple needs. Systematic screening is a key practice used to examine the overall level of students' performance for the school as a whole and identify students who may need additional supports beyond Tier 1 prevention. These integrated tiered systems emphasize equity goals by providing tiered interventions and supports at the earliest indication of need and ensure students have equitable access to core instruction in academics and social skills by using a range of positive behavior-change systems and instructional strategies. This model demonstration paper highlights the experiences of elementary schools in one district that were in the first year of an IES-funded researcher-practitioner partnership grant supporting the implementation and evaluation of their integrated tiered system of support. This brief summarizes the procedures, key findings, and lessons learned regarding conducting systematic screening at the elementary level.