The 2022 "KIDS COUNT in Colorado!" report reveals the momentous loss experienced by children and families across the state during the first two years of the COVID-19 pandemic. It illustrates the pandemic's continued, far-reaching effects on Colorado kids--from difficulty accessing health care, child care, early learning opportunities, and K-12 education; to ongoing housing instability and other economic challenges. Among Colorado households with children, about half reported a loss of household income since the pandemic began, and one-third reported difficulty paying for usual household expenses, including medical care or food. Even amid the hardships of the pandemic, however, it is clear that policy change can make an enormous difference in the lives of children and families. The 2022 report offers policy recommendations that emphasize the need to increase public investment in programs that support the health and well-being of children across the state. Recommendations include investing in income support for families; expanding access to behavioral, mental, and physical health services; and investing in sustainable, adequate support for children's early learning and development. The report also highlights policy changes enacted since March 2020 that helped shield kids and families from the pandemic and accompanying economic downturn. The annual "KIDS COUNT in Colorado!" report tracks the well-being of Colorado children statewide and at the county level. The 29th annual report includes data and research on kids in the areas of health, early childhood, K-12 education, and family economic security. The report is a complement to the national KIDS COUNT Data Book produced by the Annie E. Casey Foundation, which was released on Aug. 8. [For the 2021 report, see ED622563. For the "KIDS COUNT Data Book, 2022: State Trends in Child Well-Being," see ED625969.]