California voters decided to collect a 50 cent-per-pack tax on cigarette and other tobacco products and use the money to fund early childhood services under Proposition 10, California Children and Families First Act of 1998. In compliance to the legislative requirement of Result-Based Accountability (RBA) on the revenue spending, this report delineates evaluation findings from 39 programs that received over $8.8 million of the annual state investment in Kern County, the third largest county in California by land area. Following the RBA model, this report incorporates qualitative and quantitative analyses to present in-depth success stories and statistical results from extensive assessments of program effectiveness and service integration. A five-chapter structure is adopted to support dissemination of the multilevel findings in Fiscal Year 2021-2022 -- Built on description of the Commission leadership in Chapter 1, Chapter 2 contains assessment findings to address the results-based accountability across programs in Child Health, Family Functioning, and Child Development. Chapter 3 clarifies service partnership building in Systems of Care. Improvement of child wellbeing and family functioning is summarized in Chapter 4 to document the turning the curve process on important indicators of child wellbeing and parent support. The report concludes in Chapter 5 with a review of past recommendations and an introduction to new recommendations for next year. Netdraw, Quanteda in R, SAS and SPSS packages are employed to support data visualization, text analytics, and statistical computing. The report includes two appendices, 33 figures, 77 tables, and 151 reference items. [For "First 5 Kern Annual Report 2020-2021," see ED618879.]