Community colleges report general opening spring term enrollment figures to the Illinois Community College Board using a brief web-based survey. These figures reflect student enrollments as of the end of registration for the Spring 2022 semester--usually the 10th day of the term. Community colleges in Illinois serve a racially and ethnically diverse student population ranging in age and from varying economic conditions. Safe, innovative, and flexible course offerings and formats to meet student needs in the variety of programs offered at community colleges continued in the Spring 2022 term. Still, with community colleges serving a substantial number of at-risk students, the pandemic has heightened issues for that population ranging from fiscal to technological to emotional, and impacted enrollment statewide. Overall, compared to the same term one year ago, statewide Spring 2022 headcount enrollments and full-time equivalent (FTE) enrollments continue to be affected by COVID-19. Table 1 contains comparative statewide spring tenth-day enrollments for the last five years. Table 2 provides a comparison of fiscal year 2018 through fiscal year 2022 spring headcount enrollments for each community college. Table 3 contains a comparison of full-time equivalent (FTE) enrollments for the same five-year period. Table 4 provides fiscal year 2018 through fiscal year 2022 spring opening course enrollments (duplicated) in internet-based courses at each community college. Table 5 provides fiscal year 2022 spring opening enrollments by instructional program area. Table 6 provides opening headcount enrollments of dual credit students in Spring 2022. [For the 2021 report, see ED611291.]