Clinical Question: Do young adults with ASD (P) who receive language + vocational training (I) as opposed to language-only training (C) experience an increase in gainful employment postgraduation (O)? Method: Systematic Review. Study Sources: CINAHL Complete and PsycInfo® via EBSCOhost, American Speech-Language-Hearing Association (ASHA) journals, Google Scholar. Search Terms: ASD OR autism spectrum disorders AND employment OR independence OR young adult OR vocational OR communication OR language. Number of Included Studies: 10. Primary Results: Several studies investigated the effectiveness of targeted vocational intervention on improving employability and job performance. Seven out of the 10 included a language component in intervention. Conclusion: Current evidence suggests that when effective communication is explicitly taught, in addition to targeted vocational skills, outcomes are maximized for independence into adulthood. The effects of vocational skills are augmented particularly in interpersonal skills in targeted intervention. [Cover title varies: "The Effectiveness of Language and Vocational Training on Gainful Employment in Young Adults with Autism Spectrum Disorders. EBP Briefs. Volume 15, Article 6."]