Arizona Autism Charter School (AZACS), a public charter school for K-12 students, opened in 2014 to provide individualized education for students with autism and other disabilities alongside typically developing peers. During the COVID-19 pandemic, leaders moved quickly to adapt instruction to online and hybrid models, coordinate comprehensive services, and maintain supports. AZACS embraced flexibility and responsiveness, which has served it well--and has proven critical to meeting the needs of individual students during the pandemic. Interviews with staff and families showed how educators were able to create individualized supports for students through nimble, out-of-the-box thinking and implementation. The lessons learned from pandemic responses in schools like AZACS offer enduring lessons about fluid and effective practices that meet the needs of all students. These lessons can serve as a model and impetus for change for the benefit of all students.