This report looks at the uptake of General Certificate of Secondary Education (GCSE) (and International General Certificate of Secondary Education (IGCSE)) subjects in England in 2015. The data for these analyses were taken from the National Pupil Database (NPD). This is a database held by the Department for Education, consisting of results for all students in all subjects in schools and colleges in England, as well as pupil and school background characteristics such as age, gender, ethnicity and level of deprivation. For the analysis of uptake at GCSE the Key Stage 4 (KS4) extract of the NPD was used, consisting of all students who were at the end of KS4 in 2015 (i.e. in year 11). Uptake in this report is defined as the percentage of these students taking a GCSE in the subject, and includes exams taken by these students in previous years. Uptake of GCSEs in this report is presented by different student classifications: gender, school type, prior attainment, school gender and deprivation level. In the tables in this report, the numbers of students in each of the classifications are presented. [For the 2014 report, see ED621979.]