The purpose of the current study was to examine the validity and diagnostic accuracy of the "Intervention Selection Profile-Social Skills" (ISP-SS), a brief social skills assessment tool intended for use with students in need of Tier 2 intervention. Participants included 160 elementary and middle school students who had been identified through universal screening as at risk for behavioral concerns. Teacher participants (n = 71) rated each of these students using both the ISP-SS and the "Social Skills Improvement System -- Rating Scales" (SSiS-RS), with the latter measure serving as the criterion within validity and diagnostic accuracy analyses. Confirmatory factor analysis supported ISP-SS structural validity, indicating ISP-SS items broadly conformed to a single 'Social Skills' factor. Follow-up analyses suggested ISP-SS broad scale scores demonstrated adequate internal consistency reliability, with hierarchical omega coefficient equal to .86. Correlational analyses supported the concurrent validity of ISP-SS items, finding each ISP-SS item to be moderately or highly related to its corresponding SSiS-RS subscale. Finally, analyses indicated three of the seven ISP-SS items demonstrated sufficient diagnostic accuracy; however, findings suggest additional revisions are needed if the ISP-SS is to be appropriate for use in schools. Implications for practice and future research are discussed. [This paper was published in "Psychology in the Schools" (EJ1207669).]