In-person college advising programs generate large improvements in college persistence and success for low-income students but face numerous barriers to scale. Remote advising models offer a promising strategy to address informational and assistance barriers facing the substantial majority of low-income students who do not have access to community-based advising, yet the existing evidence base on the efficacy of remote advising is limited. We present a comprehensive, multi-cohort experimental evaluation of CollegePoint, a national remote college advising program for high-achieving low- and moderate-income students. Students assigned to CollegePoint are modestly more likely (1.3 percentage points) to attend higher-quality institutions. Results from mechanism experiments we conducted within CollegePoint indicate that moderate changes to the program model, such as a longer duration of advising and modest expansions of the pool of students academically eligible to participate, do not lead to larger program effects. We also capitalize on across-cohort variation in whether students were affected by COVID-19 to investigate whether social distancing required by the pandemic increased the value of remote advising. CollegePoint increased attendance at higher-quality institutions by 3.2 percentage points for the COVID-19-affected cohort.