Since the onset of the COVID-19 crisis, public colleges and universities have prioritized the health and safety of students, faculty, staff and visitors while continuing to offer an exceptional, affordable learning environment. Public higher education has been agile and responsive. In March 2020, the state system institutions transitioned more than 173,000 students from in-person instruction to alternative or online instruction, with limited exceptions for certain labs and practicums. These institutions added over 4,800 more nurses, doctors and other credentialed allied health professionals to the state's health care workforce during the COVID-19 crisis in spring 2020. This annual report reflects significant progress as a state system, continued commitment to excellence and innovation, and strong partnerships with common education, CareerTech, and the business community to meet Oklahoma's workforce needs. No other entity in state government drives economic growth and strengthens workforce development as directly and comprehensively as public higher education. There is no better investment to move Oklahoma forward in this dynamic, global economy. The following contents are included in this annual report: (1) Role of the State Regents; (2) Higher Education Update; (3) Strategic Direction; (4) Higher Education in Oklahoma; (5) Academics; (6) Financial Aid; (7) Student Preparation; (8) Economic Development; (9) Fiscal; (10) Institutional Highlights; and (11) Administrative Organization. [For the 2019 report, see ED609065.]