The Collaborative for Academic, Social, and Emotional Learning (CASEL) has produced a five-brief series documenting insights from their efforts to understand how educators and researchers can build relationships that support a shared action research agenda around social and emotional learning (SEL). It shares the perspectives of researchers and practitioners on developing and sustaining collaborative inquiry in classrooms, schools, districts, and states. This brief offers insights from the Research-Practice Partnership (RPP) between the Minneapolis Public Schools district (MPS) and CASEL. These insights highlight important considerations for RPPs focused on integrating continuous improvement in the implementation of systemic SEL.