Data reveals that significant opportunity and achievement gaps persist between Wisconsin's students of color and white students, native and nonnative English-speaking students, and students with and without disabilities. In 2010, the Wisconsin Department of Public Instruction identified Response to Intervention (RtI) as a way to begin to address these disparities. RtI helps schools and districts systematically provide students with supports at increasing levels of intensity based on the students' responsiveness to instruction and intervention. The Wisconsin Department of Public Instruction, in collaboration with the CESA Statewide Network, established the Wisconsin RtI Center/Positive Behavioral Intervention and Supports (PBIS) Network to assist schools and districts as they work to implement this practice. Since its inception in 2010, the Center has had great success and more than half of the schools in Wisconsin access this valuable resource. This report, a revision to "Wisconsin Response to Intervention: A Guiding Document," draws on what has been learned since 2010 - from expanding research in this field and a deepened understanding of the science surrounding successful implementation, to the feedback and success stories from Wisconsin schools as they develop an equitable multi-level system of supports based on the needs and assets within their school communities. "Wisconsin's Framework for Equitable Multi-Level Systems of Supports" is intended for all those providing, leading and supporting education in Wisconsin. This report provides a big picture view of equitable multi-level systems of supports. When localized and implemented with fidelity, this framework increases the likelihood Wisconsin schools and districts realize and sustain the best positive outcomes for every learner they serve. While this is not a how-to document, resources are provided in the Entry Points section to help get started with, or deepen implementation of, an equitable multi-level system of supports. [This report was developed with the Wisconsin RtI Center. For "Wisconsin Response to Intervention: A Guiding Document," see ED520347.]