Occupations related to science, technology, engineering and mathematics (STEM) are generally associated with high pay and contribute to the development of new technology. Continued growth is expected for STEM occupations, which would provide STEM-educated workers with additional labour market opportunities. However, less is known about the extent to which STEM graduates enter into and remain in STEM occupations in Canada. This study uses data from the 2006 and 2016 longitudinal census files to examine the occupational pathways of women and men with postsecondary credentials in STEM fields. Generally, male STEM graduates were more likely than female STEM graduates to be employed in a STEM occupation. The occupational pathways of male and female STEM graduates also differed. Among STEM graduates who were employed in a STEM occupation in 2006, women were more likely than men to have moved to a non-STEM occupation by 2016. Younger STEM graduates were more likely to exit a STEM occupation than older graduates, and men and women with college-level STEM credentials were more likely to leave a STEM occupation than their counterparts with a bachelor's degree. Some differences in the occupational mobility of men and women with STEM credentials were associated with their field of study. For example, men who studied mathematics or computer and information sciences were less likely than their counterparts who studied engineering or engineering technology to exit a STEM occupation between 2006 and 2016. However, there was no statistically significant difference in the likelihood of leaving a STEM occupation among women who had studied in these two fields. Lastly, the wage growth of male and female STEM graduates who persisted in a STEM occupation between 2006 and 2016 was not significantly different from the wage growth of their counterparts who had moved from a STEM occupation to a non-STEM occupation. [This study was funded by the Department for Women and Gender Equality.]