The Center on Standards, Alignment, Instruction, and Learning (C-SAIL), funded by the Institute of Education Sciences, examines how college- and career-readiness (CCR) standards are implemented, if they improve student learning, and what instructional tools measure and support their implementation. This brief presents findings from C-SAIL's Implementation Study, which uses interview and survey data to explore how district administrators, principals, and teachers are understanding, experiencing, and implementing Massachusetts Curriculum Frameworks in English language arts (ELA) and math. C-SAIL examines e how and what kinds of supports are provided to teachers of all students, including students with disabilities (SWDs) and English learners (ELs) who take the general state assessment. Since their research began in 2015, C-SAIL researchers have interviewed 10 state officials, and 12 district officials in six Massachusetts districts. They also conducted 12 interviews and focus groups with teachers, principals, and instructional coaches in one of these districts. They selected the six case study districts by identifying two urban, two suburban, and two rural districts with relatively high percentages of SWDs and ELs. They also examined other district characteristics--percentage of students receiving free or reduced-price lunch, student achievement or growth rates, and geographic location within the state--to ensure that their districts represented a range of contextual factors. In this brief, they highlight key insights from the six case study districts, emphasizing Massachusetts innovative practices and notable challenges.