How can we dramatically increase the number of low income young people who graduate high school and earn a postsecondary credential by age 25? One strategy that reaches beyond traditional education boundaries is gaining traction: broad regional partnerships that bring together K-12 school districts and higher education with workforce development, business, and community-based organizations. Jobs for the Future (JFF) and the James Irvine Foundation were among those investing in cross-sector partnerships through creation of the Linked Learning Regional Hubs of Excellence in 2015. The goal, over three years, was to significantly increase the number of California graduates from innovative Linked Learning pathways that blend high school, college, and career. This brief describes the evolution of the Linked Learning Regional Hubs of Excellence and the points of momentum they achieved in transforming an array of individual programs into productive regional systems. It is a summary of multiple years of learning and culminating reflections from the JFF team that supported the Hubs. This is one of two briefs summarizing lessons learned in the Linked Learning Regional Hubs of Excellence about improving student success in high school, college, and careers through systems change in California. The other brief, "How to Lead Systems Change for Student Success: Developing 6 Qualities of Effective Cross-Sector Leadership," examines how to cultivate the leadership qualities that are key to creating high-performing regional systems. [For "How to Lead Systems Change for Student Success: Developing 6 Qualities of Effective Cross-Sector Leadership," see ED593999.]