The European Forum for Enhanced Collaboration in Teaching (EFFECT) project explored how pedagogical staff development and learning and teaching developments in general could be enhanced and supported through European-level action. EFFECT is an Erasmus+ KA3-funded project (2015-2019). It was developed by a diverse consortium of 12 partners, coordinated by the European University Association (EUA). The consortium brought together major European stakeholder organisations, specialised university networks, national organisations representing higher education institutions, individual universities, as well as professional organisations specialised in teaching enhancement. In addition, EFFECT was able to involve representatives from non-university higher education institutions in various activities and meetings, as well as experts who were seconded by partners, or associated with the project during its lifetime. The EFFECT Consortium primarily aimed at assessing the feasibility of a European-level approach to teaching enhancement. Instead of focusing on a brick-and-mortar academy, EFFECT explored ways of facilitating European-level exchange and effective collaboration for the enhancement of learning and teaching. EFFECT approached teaching enhancement as part of a broader change agenda that institutions have to embrace. Teaching enhancement cannot be an isolated measure towards "better teaching", but must be embedded into institutional, strategic and systematic approaches for learning and teaching, linked to other higher education mission goals, in particular to research, and supported by the governance and management system. Hence, EFFECT simultaneously worked on approaches for enhancing teaching staff development and institutional strategies for learning and teaching, with the underlying idea that individual and institutional levels need to be interconnected in order to enhance learning and teaching. Subsequently, the project was structured following three strands: (1) Exploring the feasibility of a European-level offer for teaching enhancement courses; (2) Supporting the development of institutional approaches on learning and teaching; and (3) Developing approaches for a European initiative for teaching enhancement, based on the results from the two previous strands. This publication summarises the main outcomes and lessons learnt from the EFFECT project. [Co-funded by the Erasmus+ Programme of the European Union.]