The Global Partnership for Education (GPE) supports country-level efforts for equity and quality in education through school health activities. In developing countries, an estimated 500 million days of school per year are lost due to sickness. Poor health conditions of school children in developing countries hinder their access and participation in school. School health programs can prevent and treat common childhood conditions and, thus, increase participation in school. GPE's approach includes: (1) Targeting support to the poorest and most marginalized children through school health activities; (2) Strengthening countries' capacity to design and implement comprehensive school health policies; (3) Encouraging partner countries to open their schools for health service delivery to support improved student health; (4) Supporting countries to provide a safe learning environment, including access to water for drinking and washing and sanitation and hygiene facilities; (5) Sharing evidence, good practice and costing of priority health services with partner countries; and (6) Providing funding to train educators to carry out school-based health activities. Examples from Cambodia, Ethiopia, and Haiti are presented.