This research study investigated whether the effects of response to intervention impacted student achievement in a rural virtual high school, as well as sought to determine staff perceptions of the efficacy of the implementation of RTI within the school. The researcher used both quantitative and qualitative analysis to effectively answer the question. The researcher utilized two formative assessment methods; the school's curriculum and intervention platform; Edmentum-PLATO, and the District's Benchmark Assessment; Aimsweb. Results showed strong significance that the treatment group's posttest scores significantly increased as compared to the comparison group with both intervention assessment methods. Staff perceptions concluded that if teachers are effectively trained and if the intervention is implemented with fidelity; student achievement is highly likely. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://bibliotheek.ehb.be:2222/en-US/products/dissertations/individuals.shtml.]