This document is the first in a series of products that will be developed under the knowledge production service area of the National Center on Intensive Intervention (NCII), with the purpose of describing and communicating the results of research on intensive intervention. The synthesis studies summarized here, and others to be identified, will inform the development of a concept paper about intensive intervention. The concept paper will be produced in multiple formats to reach a diverse range of stakeholders. These products will be produced within the first year of NCII's operation. The purpose of this deliverable is to identify and describe major synthesis studies that have been conducted to date regarding the effectiveness of intervention strategies targeting students with disabilities who have intensive academic or behavioral needs. NCII senior advisors identified the synthesis studies, which are considered the most comprehensive and informative for the purpose of NCII. However, the studies identified do not necessarily reflect all of the synthesis work that has been conducted in the area of intensive academic and behavioral intervention. We will continue to identify and review synthesis studies as appropriate and add to this annotated bibliography during the course of NCII's operation. The following annotations are organized into four topic areas: (1) Reading, (2) Mathematics, (3) Behavior, and (4) Data-Based Individualization. The annotations include the following information about each synthesis report: citation, abstract, studies included (number of studies, years included, grades included, search procedures, and study selection criteria), synthesis methods, and synthesis results.