Homeless youth and youth in foster care are often unprepared for the transition to adulthood. Given the economic benefits of college, the Government Accountability Office (GAO) was asked to examine the college experiences of these vulnerable youth. GAO examined: (1) college enrollment and completion for foster and homeless youth; (2) the extent to which challenges these youth face affect their ability to pursue college; and (3) the extent to which program barriers hinder these youth from obtaining federal financial assistance for college. GAO analyzed the most recently available Education data--two enrollment data sets, for 2011-2012 and 2013-2014, and data on college completion from 2009; reviewed relevant federal laws and guidance; interviewed officials from the Department of Education and the Department of Health and Human Services, as well as external groups knowledgeable about higher education, foster youth, and homelessness; and held discussion groups with foster and homeless youth. GAO is making six recommendations to the Departments of Education and Health and Human Services to improve homeless and foster youth access to financial assistance for college, including centralizing college information for these youth on the Department of Education's website, clarifying the Department of Education guidance, and considering legislative proposals to simplify federal requirements for homeless and foster youth. The Department of Health and Human Services agreed with these recommendations, while the Department of Education generally did not agree or disagree, but described actions it was taking in response to the recommendations. Appended are: (1) Objectives, Scope, and Methodology; (2) College Enrollment and Completion of Foster Youth and Unaccompanied Homeless Youth Compared to Dependent Students; (3) Comments from the U.S. Department of Education; (4) Comments from the U.S. Department of Health and Human Services; and (5) GAO Contact and Staff Acknowledgments.