Mobile tablets are becoming more prevalent in educational settings, but little is known about the impact of using technology-infused curricula in preschool classrooms. The research summarized in this brief suggests that well-designed tablet-based activities can indeed improve student learning outcomes at the preschool level. These positive outcomes are more likely when digital activities target clear learning goals; are collaborative and social experiences; are accompanied by hands-on activities; and are used in classrooms where teachers receive support for their integration. [This brief was produced as part of the Research + Practice Collaboratory (RPC).]