In the face of budgetary constraints, new marketplace competition, digital innovation and an emerging generation of students with new demands and new needs, higher education in America is challenged as never before. This paper reviews the various challenges facing traditional non-profit educational institutions, considers the potential of an online, technology-mediated curriculum, reviews Constructivist Pedagogical Theory as a viable tool for faculty at traditional non-profit institutions and presents findings from a case study of a technology-mediated, hybrid course inspired by Constructivist Theory. [For the full proceedings, see ED562107.]