Replacing lecture-based learning content with online information can augment learner-content interaction and facilitate greater mastery over a subject. The success of online delivery will depend on the readiness of learners to use and accept technology as well as the readiness of the organizational infrastructure to support a learner-centric learning culture. Successful implementation and adoption of online learning can be indicated by technology acceptance. In this project, lecture-based learning content for a healthcare vocational training course in West Africa was replaced with e-learning and applied to learners who had little or no prior computer experience. E-learning content was combined with practical and peer-based pedagogy to provide a blended learning course. This paper describes the acceptance of technology-assisted learning during the project. [For the complete proceedings, see ED557189.]