School systems across the world are facing a plethora of global changes that dictate rethinking instructional practices and professional leadership roles. School reformers are constantly facing the challenges dictated by the universal culture that exerts a huge power on learning and teaching, and leading. This article introduces a comprehensive framework for leaders who seek to achieve equity and social justice in the diverse schools. Drawing on pertinent research and literature in the field, the discussion introduces a comprehensive, equitable and culturally responsive, leadership model conducive to producing promising educational outcomes. Implications for school reform are drawn while suggesting specific guidelines and ingredients for educational success.