To meet the more rigorous expectations embodied in new college- and career-ready standards, students will need teachers who teach in ways that are distinctly different than how most have been teaching. Students will need, for example, English and science teachers who give students more guided practice in reading nonfiction texts that are more complex than ever. Students will need mathematics teachers who cover fewer topics more deeply and who emphasize conceptual understanding with more intense application as well as procedural skill and fluency. Students will need teachers who continually work to deepen their own knowledge of the content so that they can help their diverse students make multiple connections to the standards. Students will need teachers who can work and learn together to sustain continuous improvement to ensure that "all" students have opportunity to learn at high levels. To ensure that students have such teachers, in addition to high-quality aligned curricular resources, materials, and tools, high-quality opportunities for teachers to learn to meet the demands of college- and career-ready standards are crucial. The purpose of this Research-to-Practice Brief is to describe the elements necessary to align state-level policies and practices with one another and to move away from professional development and to move toward professional learning so that more teachers in more schools have access to the conditions, incentives, and the opportunities for engaging in professional learning that is less fragmented and more coherent, more relevant, and better differentiated. In this brief, the author discusses how state-level professional development policy, teacher certification policy, teacher evaluation policy, and teacher compensation policy can come together to build systems to support true professional learning. Throughout the brief, the author provides examples of states that are beginning to take important steps toward ensuring that all teachers are ready and able to prepare their students for college and careers in the 21st century. Tool 1: Prompts for Finding Ways to Make Professional Learning More Systemic in Your State is appended. (Contains 2 figures.)