Across the country, resource-strapped school districts are looking for opportunities to work strategically with other districts to increase efficiencies and learn from each other's experiences. The Fresno-Long Beach Learning Partnership, established in 2008, serves as a useful example of such collaboration. The overarching goal of the Partnership is to graduate students prepared for success in higher education or for a career with significant growth potential. With this goal in mind, the third and fourth largest districts in California identified three major areas of focus for their joint endeavors: enhancing mathematics instruction, improving outcomes for English learners (ELs), and developing strong leaders at the school and district levels. In 2011, they added a fourth focus--college and career readiness--to leverage additional strategies underway within each district. In their first two briefs describing the Fresno-Long Beach Learning Partnership, the authors used Etienne Wenger's (1998) communities of practice framework to describe the initial stages of the Partnership and its role in developing district-level leadership. Here, they look more deeply at two specific areas of focus for the Partnership--mathematics and ELs. Both of these areas provide insights for other jurisdictions considering similar cross-system efforts. (Contains 9 exhibits and 13 endnotes.)