Potential first-generation students make up a large segment of Wisconsin's teenage population. To increase the pool of educated workers in Wisconsin, policymakers must work to recruit, retain, and graduate these students. Estimates of the size of the first-generation student population in the state are crucial for these efforts. This brief presents a first-of-its- kind method for estimating the number of potential first-generation students in Wisconsin, discusses the primary characteristics of this population, and provides implications for policymakers and practitioners. (Contains 2 tables, 1 figure and 12 notes.)