The comprehension of interdependent complex systems, which is part of state and national standards, is an enormous challenge for learners. In traditional physiology teaching materials, which structure the human body into decoupled subsystems (e.g., respiratory and cardiovascular) isolated in separate chapters, there is a ubiquitous absence of explanations for how systems "interact." These interactions, central to understanding how the human body works, have been largely ignored because of the inadequacy of traditional teaching media. "Collective Simulations" address this by creating an immersive inquiry-science learning environment that lets students collaboratively "experience" system interactions. (Contains 1 figure.)