Given the prevalence of alcohol and other drug abuse and violence on campuses and in communities, programs and coalitions developed to prevent or intervene in these problems are faced with a challenging and long-term task. While the development of coalitions or campus-based prevention programs is a healthy start, these efforts must be sustained over time to have a truly lasting effect. Sustainability can seem a daunting task in the midst of implementing programs or mobilizing a coalition; however, by incorporating sustainability into all aspects of prevention efforts (assessment, planning, implementation, and evaluation), it becomes an achievable goal. This emphasis on sustainability will actually strengthen prevention efforts from the beginning. This publication is organized into two basic sections. The first emphasizes the need to include sustainability in assessment, planning, and evaluation. The final section focuses on mechanisms for developing and promoting sustainable programs and coalitions. Each aspect plays a role in overall sustainability. This paper presents suggestions for program and coalition sustainability that have been synthesized from publications, Web sites, and personal experiences shared by colleagues across the country. (Contains 3 resources.)