This handbook was prepared to help science teachers, administrators, and other school staff members understand and avoid situations in which accidents might occur in the science laboratory, on field trips, or during outdoor education experiences. Suggestions contained in this publication are generally agreed upon and recommended for consideration by all California science teachers. Because this publication was prepared for statewide distribution, not all of the recommended policies are appropriate for adoption in all school districts. Ideas may be adapted to meet the needs of teachers and students in each district. This publication is designed for use by laboratory instructors and therefore provides minimal information directed towards students, parents, and administrators about necessary safety procedures in the science laboratory. Some materials such as parental consent forms and sample student safety contracts have been included in the appendices to help teachers communicate with other audiences. Topics include: (1) "First Aid"; (2) "General Laboratory Safety Precautions"; (3) "Safety in the Biology Laboratory"; (4) "Safety in the Chemistry Laboratory"; (5) "Safety in the Physics Laboratory"; and (6) "Safety Practices". (Author/SOE)