This study collected information on girls in San Francisco, California in the areas of demographics, economics, education, health, safety and violence, and criminal justice. Data came from local, state, and national sources (e.g., the U.S. Census Bureau; the California Bureau of Justice and the Criminal Statistics Center; the California Department of Education; and the California Department of Health Services; the San Francisco Unified School District; the San Francisco Housing Authority; and the San Francisco Department of Human Services). Findings highlight how few and diverse San Francisco girls are. San Francisco has the smallest percent of youth of any California county, and in 2000, San Francisco girls numbered about 55,000. Approximately 79 percent of all girls age 10-17 are girls of color, 7 percent of girls live in poverty, and 10 percent of public high school girls are lesbian, bisexual, or sexual orientation unknown. Most girls graduate high school. However, in 2002, most high school girls taking the California High School Exit Exam failed. San Francisco's girls face complex social and environmental challenges that affect their physical and mental wellbeing. Rates of sexually transmitted diseases are much higher for girls than boys. Most girls are dissatisfied with their weight and not meeting fitness standards. Most girls do not take drugs. High numbers report being depressed. Minority girls are disproportionately represented in the child welfare and juvenile justice systems. A list of online statistical resources is appended.(Contains over 300 footnotes and 113 figures.) (SM)