This guide was prepared while working with many Massachusetts schools to remove items that contain mercury and to find suitable alternatives. It contains fact sheets on: mercury in science laboratories and classrooms, mercury in school buildings and maintenance areas, mercury in the medical office and in medical technology classrooms in vocational technical schools, mercury in HVAC laboratories in vocational technical schools, establishing hazardous and universal waste collection areas, and mercury-free purchasing policies. The fact sheets contain information on items that contain mercury, non-mercury alternatives, storing unwanted items, how to handle a spill, and additional resources. (EV)