This paper asserts that the more enriching the interactions and experiences that parents and child caregivers provide to very young children, the more chances they are providing for growing neural connections and pathways in the brain to support language, reasoning, and planning skills; mental health and emotional well-being; and motor development. The paper discusses 20 ways for child care professionals to ensure optimal development of children's growing brains. Examples are: (1) be sure that the baby's brain before birth has a healthy start; (2) provide rich language inputs; (3) play simple body games; (4) make a picture book sharing a daily intimate activity; (5) share joint attention; (6) use diapering time to build babies' emotional feelings of having a "lovable body"; (7) provide developmentally appropriate toys; (8) respond promptly to infant distress signals; (9) nurture baby confidence; and (10) perform daily infant massage. (EV)