This 12-section handbook, based on information for Colorado but applicable to other states as well, contains resources and lists and explains procedures to establish or expand a career guidance center in a school, government office, or organization. The 12 sections cover the following topics: (1) purpose and philosophy; (2) assessment, advisory boards, and goals and objectives; (3) location and floor plans; (4) levels of development; (5) career assessment tools; (6) career exploration tools; (7) career center day-to-day operations; (8) presenting resources; (9) documentation, accountability, and reporting; (10) support services; (11) 38 references and resources; and (12) 13 selected ordering sources. Five appendixes contain a career center needs assessment survey for faculty and staff; a needs-assessment questionnaire for high school students; a faculty request for services form; a sample basic intake form; and a sample career center student intake form. (KC)