This paper discusses how presentation software can be used to design custom materials for a variety of people with special needs, including children and adults with low vision, people with developmental disabilities, and stroke patients with cognitive impairments. Benefits of using presentation software include: (1) presentation software gives the user enormous amount of easy control over the information displayed and allows users to insert desired text, graphics, and photographs, and determine when and where they are to appear; (2) it can enhance the visibility of materials to address the individual needs of low vision viewers; (3) PowerPoint lets users manipulate contrast by using black and white, shades of gray, or color combinations to address various visual disorders; (4) sound can be incorporated into presentations; (5) graphics can be used to focus students' attention and stimulate discussion; (6) PowerPoint can be used to flash text or graphics at any of three speeds; (7) PowerPoint can be used to display presentation slides on a large screen or monitor to provide a way to discuss information with an entire class; and (8) results of art therapy can be scanned, incorporated into a presentation file, and then featured in a variety of formats. (CR)