Applied research is supposed to take the perspective with the highest degree of corroboration as a basis for action. The realm of organizational perspectives is characterized, however, with a multitude of competing research programs, seldom tested against each other. Epistemological and methodological issues overwhelm inquiry in applied research. This report reflects the major topics of the theory of knowledge in relation to organizational perspectives. Since a rationale for selecting among perspectives is needed, it is argued that the falsificationist approach is better than any other theory of knowledge for overcoming the major problems of the domain. Analysis, diagnosis, design, and implementation are the successive stages of the organizational change process. Design-oriented research, testing the developed design in comparable organizational situations, is compatible with the positivist approach to science. It is also stressed that researchers may enhance the impact of their work by taking into account criteria of usefulness and clarity. Three schemes (figures) illustrate the discussion. (Contains 40 references.) (SLD)