This publication presents four major research papers on college campus substance abuse prevention and research with reviews of the papers by practitioners in the substance abuse prevention field. Following a Preface and Introduction, the first paper is "Theories, Dominant Models, and the Need for Applied Research" by Gerardo M. Gonzalez. It examines the lack of theoretical models and theory-driven research in this area. The second paper is "Current Knowledge in Prevention of Alcohol and Other Drug Abuse" by Lewayne D. Gilchrist. This paper traces the development of current approaches to alcohol and drug abuse prevention and on the effectiveness of prevention programs for youth conducted during the last 30 years. The third paper, "The Influence of College Environments on Student Drinking" (George D. Kuh) summarizes research on environmental influences and suggests ways to create good environmental conditions. The last paper is "Assessing Collegiate Substance Abuse: Current Trends, Research Needs, and Program Applications" (Alan D.Berkowitz). This paper recommends basing survey assessment on theoretical frameworks and discusses recent attempts to standardize survey instruments and survey administration procedures. A final section offers responses by John H. Schuh ("Reactions from a Metropolitan Campus"), Bettye Ward Fletcher ("The Perspective of Historically Black Colleges and Universities"); M. Lee Upcraft ("Response from a Public University"); and William H. Barr and Judith M. Chambers ("A Private University Perspective"). Vonnie V. Clement offers "A Final Word." Each of the four main papers contains extensive references. (JB)