This guide attempts to apply research findings on children exposed to drugs during the prenatal period to practical educational considerations. Section I is an overview of the prevalence and impact of substance exposure, including chapters on the effects that prenatal substance exposure and living in a drug-abusing environment have on children. Research findings from studies on children exposed to drugs are summarized. Section II presents programs and services that are proving successful with this population. It describes federal, state, and community early intervention programs as well as training programs for both teachers and parents. Also presented are practices that foster the development of these children and specific ideas from successful programs and practices. Section III identifies a variety of classroom management and instructional strategies, including more examples of effective programs as well as a number of teaching tips. Section IV contains an annotated list of organizations, consultants, publications, and other resources of interest to practitioners and policymakers. The appendices contain information on the Drug-Free Schools Recognition Program, sample behavior modification charts, and a classroom rating scale for teachers. (Contains 120 references.) (DB)