Growing Up Strong (GUS) is a curriculum designed to develop strong mental and physical health in kindergarten through sixth grade students, with the objective of preventing subsequent substance abuse. This document contains a teacher's guide for using GUS in fourth grade classrooms (GUS 4) and duplication masters of materials that can be sent home with children to promote family involvement in GUS. Part I of the four-part teacher's guide provides background information about the program, GUS's multicultural approach and comprehensive prevention philosophy, major components of the GUS 4 program, and accessory materials. Part II includes information on using GUS, evaluating the program, and using the family involvement messages. Part III offers suggestions on classroom management, ways to teach problem solving, positive reinforcement, cooperative learning, and children's art, and lists 32 books for children, 24 books on cooperative learning for teachers, 4 publications for parents, and 23 organizational resources. Part IV provides instructional units on personal safety, drugs, stress management, refusal skills, friendship, and other topics. The units contain activities designed to help children develop social and self-management skills. The materials designed for children to take home include information sheets for parents about drugs, the importance of family and friends, physical health, parents as role models, the encouragement of children's reading, the effects of stress on children, and the creation of special times with their children. Sample awards for children and GUS promotional materials are attached. (AC)